Characteristics and Clinical Outcomes of Patients on Mechanical Ventilation in the Coronary Care Unit of a Tertiary Care Hospital in Bangladesh

Background: This study was undertaken to evaluate clinical characteristics, indications, outcomes, and factors affecting outcomes in adult patients on mechanical ventilation admitted CCU that will help planning of proper MV management programs. There are few studies the coronary care unit (CCU) population even fewer from developing countries.
 Methods: All received at Ibrahim cardiac hospital between June 2019 July 2020 were prospectively recruited. Different demographic, type characteristics ventilation, concomitant complications treatment, laboratory variables recorded initiation daily, all throughout course & thereafter.
 Results: Out 1563 CCU, 138 IMV. Mean age 64.2±12.1. Male predominant (71.7% vs. 28.3%). DM most common (81.9%) risk factor. Reasons for intubation as follows: 1 respiratory failure (40%), II (35%), post arrest (25%). Mostly used mode A/C VCV (96.4%). Invasive associated with high APACHE score, low admission PH, Po2, Pco2. A higher in-coronary death observed (65.2%) while MI (70.3%) than survivors (34.8%). CAG±PCI (5.8%) keeping or after extubation. The mean duration MV, stay (53.5±5.8, 80.5±7.6 128.8±12.0) hours respectively. main independently increased mortality (i) pre-MV factors: age, scores, acute left ventricular failure, cardiogenic shock, sepsis (64.2±12.1, 39.1±19.2, 65.9%, 81.2%, 70%). (ii) Patient during ventilation: without positive end-expiratory pressure (65.6%) (iii) Factors occurring over MV: PaO2/FiO2<100 (61.2±18.75) development renal (47.8%), VAP (40.6%), MODS (21.0%) ARDS (8.7%) MV.
 Conclusion: Outcome among mechanically ventilated depended (including patient’s demographics, nature morbidity, received, conditions MV). These may be present before develop well protocols CCU.
 Bangladesh Heart Journal 2023; 38(1): 22-31